Houben, ,T.,  Loonen, C.M., Baca, S., Schenke, M., Ferrari, M.D., Terwindt, G,  Voskuyll, R.A., Charles, A., van den Maagdenberg, A., Tolner, E. Optogenetic induction of cortical spreading depression in anaesthetized and freely behaving mice. Journal of Cerebral Blood Flow and Metabolism, 37(5):1641-1655, 2016. PDF


    Matynia A, Nguyen E, Sun X, Blixt FW, Parikh S, Kessler J, Perez de Sevilla Muller L, Habib S, Kim P, Wang ZZ, Rodriguez A, Charles A, Nusinowitz S, Edvinsson L, Barnes S, Brecha NC, Gorin MB. Peripheral Sensory Neurons Expressing Melanopsin Respond to Light. Front Neural Circuits. 2016;10:60.


    Tobis, J. M., Charles, A., Silberstein, S. D., Sorensen, S., Maini, B., Horwitz, P. A., & Gurley, J. C. Percutaneous Closure of Patent Foramen Ovale in Patients With Migraine: The PREMIUM Trial. Journal of the American College of Cardiology, 70(22), 2766-2774, 2017. PDF


    Chang, M. Y., Phasukkijwatana, N., Garrity, S., Pineles, S. L., Rahimi, M., Sarraf, D., Johnston, M., Charles, A., and Arnold, A. C. Foveal and Peripapillary Vascular Decrement in Migraine With Aura Demonstrated by Optical Coherence Tomography Angiography. Investigative Ophthalmology and Vision Science, 58(12), 5477-5484, 2017


     Diener, H.C., Charles, A.C., Goadsby, P.J., and D. Holle. New therapeutic targets in migraine treatment. Lancet Neurology.  14(10):1010-22, 2015. PDF


     Charles, A.C. and Hansen, J.M.  Migraine aura: new ideas about cause, classification, and clinical significance. Current Opinion in Neurology. 28(3):255-60, 2015.  PDF


    Charles, A.C. and Pradhan, A.  Delta opioid receptors as therapeutic targets for migraine. Current Opinion in Neurology. 29: 314-9, 2016.    PDF


    Sharav Y, Katsarava Z, Charles A. Facial presentations of primary headache disorders. Cephalalgia 37(7):714-719, 2017.


    Charles, A.  Clinical Practice: Migraine. New England Journal of Medicine 377: 553-561, 2017.  PDF


    Charles, A. The pathophysiology of migraine: implications for clinical management. Lancet Neurology, 17(2), 174-182. 2018.  PDF


    Charles, A. "Migraine." New England Journal of Medicine 377: 1698-1699, 2017.


    Charles, A.  Migraine Pathophysiology: The Aura. Continuum In Press, 2018.


    Hoffman, J., and Charles, A. Glutamate and its receptors as therapeutic targets for migraine. Neurotherapeutics In Press, 2018.



News coverage:


New York Times, September 2017